Некоторые патофизиологические механизмы нарушения сперматогенеза у пациентов с варикоцеле. Часть 1

   Несмотря на противоречивые взгляды о связи варикоцеле и патоспермии, многочисленные исследования доказали отрицательное воздействие варикоцеле на показатели сперматогенеза и ультраструктурные характеристики сперматозоидов. Исследования, проведенные в последние десятилетия, несколько изменили общий взгляд на патофизиологию развития патоспермии при варикоцеле и раскрыли роль взаимосвязанных процессов: теплового стресса, оксидативного стресса (ОС), апоптоза, генетических, воспалительных и других факторов, которые способствуют индукции патофизиологических проявлений.

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