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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">agx</journal-id><journal-title-group><journal-title xml:lang="ru">Андрология и генитальная хирургия</journal-title><trans-title-group xml:lang="en"><trans-title>Andrology and Genital Surgery</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2070-9781</issn><issn pub-type="epub">2412-8902</issn><publisher><publisher-name></publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.63769/2070-9781-2026-27-2-88-98</article-id><article-id custom-type="elpub" pub-id-type="custom">agx-893</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCHES</subject></subj-group></article-categories><title-group><article-title>Сравнение эндоскопических методов лечения гиперплазии предстательной железы у лиц пожилого возраста</article-title><trans-title-group xml:lang="en"><trans-title>Comparison of endoscopic treatment methods for prostatic hyperplasia in the elderly</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0002-9979-9301</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Куликова</surname><given-names>Е. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Kulikova</surname><given-names>E. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Канд. мед. наук, врач-уролог.</p><p>Рязань</p></bio><bio xml:lang="en"><p>Elizaveta M. Kulikova - MD, Cand. Sci. (Medicine).</p><p>Ryazan</p></bio><email xlink:type="simple">nikolconnik@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0005-8491-3775</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ломакина</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Lomakina</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ломакина Арина Алексеевна - врач-уролог.</p><p>Рязань</p></bio><bio xml:lang="en"><p>Arina A. Lomakina – MD.</p><p>Ryazan</p></bio><email xlink:type="simple">lomakina_0408@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0007-8653-4140</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ильченко</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ilchenko</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ильченко Елена Андреевна - врач-уролог.</p><p>Рязань</p></bio><bio xml:lang="en"><p>Elena A. Ilchenko – MD.</p><p>Ryazan</p></bio><email xlink:type="simple">e.1lchenko@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0008-6410-7460</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ли</surname><given-names>Д. A.</given-names></name><name name-style="western" xml:lang="en"><surname>Li</surname><given-names>D. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ли Данила Андреевич - врач-уролог.</p><p>Рязань</p></bio><bio xml:lang="en"><p>Danila A. Li - MD.</p><p>Ryazan</p></bio><email xlink:type="simple">dannyonthestreet1@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0003-3853-0875</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Житина</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhitina</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Житина Екатерина Вячеславовна - врач-уролог.</p><p>Рязань</p></bio><bio xml:lang="en"><p>Ekaterina V. Zhitina - MD.</p><p>Ryazan</p></bio><email xlink:type="simple">katrin.zhitina@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0007-9432-3546</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хамробоев</surname><given-names>Н. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Khamroboev</surname><given-names>N. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Хамробоев Назиф Насимжонович - врач-уролог.</p><p>Рязань</p></bio><bio xml:lang="en"><p>Nazif N. Khamroboev – MD.</p><p>Ryazan</p></bio><email xlink:type="simple">nazifhamroboev@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0004-6464-702X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жучкова</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhuchkova</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Жучкова Арина Сергеевна - врач-уролог.</p><p>Рязань</p></bio><bio xml:lang="en"><p>Arina S. Zhuchkova – MD.</p><p>Ryazan</p></bio><email xlink:type="simple">sdobnikova.arina@bk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0005-1830-1797</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чернышева</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Chernysheva</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Чернышева Виктория Андреевна - врач-уролог.</p><p>Рязань</p></bio><bio xml:lang="en"><p>Victoria A. Chernysheva – MD.</p><p>Ryazan</p></bio><email xlink:type="simple">zavalishina.vicktoria@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0009-2690-0561</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Трушкова</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Trushkova</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Трушкова Анна Алексеевна - врач-уролог.</p><p>Рязань</p></bio><bio xml:lang="en"><p>Anna A. Trushkova – MD.</p><p>Ryazan</p></bio><email xlink:type="simple">trushkovaaa@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0000-4785-0465</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алексанян</surname><given-names>Т. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Aleksanyan</surname><given-names>T. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Алексанян Тигран Комитасович - врач-уролог.</p><p>Рязань</p></bio><bio xml:lang="en"><p>Tigran K. Aleksanyan - MD.</p><p>Ryazan</p></bio><email xlink:type="simple">tigran.a2002@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0009-2387-568X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Давтян</surname><given-names>Г. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Davtyan</surname><given-names>G. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Давтян Генри Грачьяевич - врач-уролог.</p><p>Рязань</p></bio><bio xml:lang="en"><p>Genrikh G. Davtyan - MD.</p><p>Ryazan</p></bio><email xlink:type="simple">henri.1999@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0006-6455-0396</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шаршев</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Sharshev</surname><given-names>A. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шаршев Алмаз Муратович - врач-уролог.</p><p>Рязань</p></bio><bio xml:lang="en"><p>Almaz M. Sharshev - MD.</p><p>Ryazan</p></bio><email xlink:type="simple">almaz.sharshev@icloud.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0001-3370-3517</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Даниелян</surname><given-names>М. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Danielyan</surname><given-names>M. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Даниелян Мэри Гарниковна - врач-уролог.</p><p>Рязань</p></bio><bio xml:lang="en"><p>Meri G. Danielyan - MD.</p><p>Ryazan</p></bio><email xlink:type="simple">Maruique9@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Рязанский государственный медицинский университет им. акад. И.П. Павлова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Ryazan State Medical University named after Academician I.P. Pavlov</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>06</day><month>09</month><year>2026</year></pub-date><volume>27</volume><issue>2</issue><fpage>88</fpage><lpage>98</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Куликова Е.М., Ломакина А.А., Ильченко Е.А., Ли Д.A., Житина Е.В., Хамробоев Н.Н., Жучкова А.С., Чернышева В.А., Трушкова А.А., Алексанян Т.К., Давтян Г.Г., Шаршев А.М., Даниелян М.Г., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Куликова Е.М., Ломакина А.А., Ильченко Е.А., Ли Д.A., Житина Е.В., Хамробоев Н.Н., Жучкова А.С., Чернышева В.А., Трушкова А.А., Алексанян Т.К., Давтян Г.Г., Шаршев А.М., Даниелян М.Г.</copyright-holder><copyright-holder xml:lang="en">Kulikova E.M., Lomakina A.A., Ilchenko E.A., Li D.A., Zhitina E.V., Khamroboev N.N., Zhuchkova A.S., Chernysheva V.A., Trushkova A.A., Aleksanyan T.K., Davtyan G.G., Sharshev A.M., Danielyan M.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://agx.elpub.ru/jour/article/view/893">https://agx.elpub.ru/jour/article/view/893</self-uri><abstract><sec><title>Обоснование</title><p>Обоснование. Доброкачественная гиперплазия предстательной железы является одним из наиболее распространенных урологических заболеваний у мужчин пожилого и старческого возраста и нередко сопровождается выраженными симптомами со стороны нижних мочевыводящих путей. С учетом старения населения эта патология приобретает все бóльшую медико-социальную значимость.</p><p>Хирургическое лечение остается основным методом коррекции инфравезикальной обструкции при неэффективности медикаментозной терапии. В последние годы широкое распространение получили эндоскопические методы лечения, отличающиеся меньшей травматичностью и возможностью применения у пациентов с сопутствующей соматической патологией.</p><p>В то же время выбор оптимального эндоскопического метода у лиц пожилого возраста требует учета клинических особенностей, объема предстательной железы и риска послеоперационных осложнений, что определяет актуальность сравнительной оценки различных хирургических подходов.</p><p>Цель исследования – сравнить клиническую эффективность и безопасность различных эндоскопических методов хирургического лечения доброкачественной гиперплазии предстательной железы у пациентов пожилого возраста.</p></sec><sec><title>Методы</title><p>Методы. В исследование включены пациенты пожилого возраста с клинически и инструментально подтвержденной доброкачественной гиперплазией предстательной железы, которым выполнены эндоскопические оперативные вмешательства. В зависимости от метода лечения пациенты распределены на группы. Всем больным проводили стандартное клинико-лабораторное обследование, ультразвуковую оценку объема предстательной железы и остаточной мочи, а также анализ выраженности симптомов со стороны нижних мочевыводящих путей. Статистическую обработку данных выполняли с использованием параметрических и непараметрических методов, различия считали статистически значимыми при p &lt;0,05.</p></sec><sec><title>Результаты</title><p>Результаты. Эндоскопические методы хирургического лечения обеспечивали статистически значимое снижение выраженности симптомов со стороны нижних мочевыводящих путей, улучшение уродинамических показателей и снижение объема остаточной мочи. Выявлены различия по продолжительности операции, срокам катетеризации и частоте осложнений между сравниваемыми методами.</p></sec><sec><title>Заключение</title><p>Заключение. Полученные результаты подтверждают эффективность различных эндоскопических методов лечения доброкачественной гиперплазии предстательной железы и указывают на необходимость индивидуального выбора хирургической технологии с учетом объема предстательной железы, клинического состояния пациента и опыта хирургической команды.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>BACKGROUND</title><p>BACKGROUND: Benign prostatic hyperplasia is a common condition in older men, often causing significant symptoms that negatively impact quality of life. Due to the aging population, this condition is becoming increasingly important from a medical and social perspective. Surgical interventions, particularly endoscopic ones, remain the primary treatment option when drug therapy is ineffective, as they are less invasive and can be used in patients with comorbidities. However, choosing the most appropriate endoscopic method for elderly patients requires consideration of their clinical characteristics and potential risks of postoperative complications, highlighting the need for a comparative evaluation of various surgical approaches to achieve optimal outcomes</p></sec><sec><title>AIM</title><p>AIM: To compare clinical efficacy and safety of different endoscopic surgical methods for the treatment of benign prostatic hyperplasia in elderly patients.</p></sec><sec><title>METHODS</title><p>METHODS: The study included elderly patients with clinically and instrumentally confirmed benign prostatic hyperplasia who underwent endoscopic surgical treatment. Patients were divided into groups depending on the surgical technique used. All patients underwent standard clinical and laboratory examinations, ultrasound assessment of prostate volume and postvoid residual urine, and evaluation of lower urinary tract symptoms. Statistical analysis was performed using parametric and non-parametric methods; p &lt;0.05 was considered statistically significant.</p></sec><sec><title>RESULTS</title><p>RESULTS: Endoscopic surgical techniques led to a significant reduction in lower urinary tract symptoms, improvement in urodynamic parameters, and decrease in postvoid residual urine. Differences were observed in operative time, duration of catheterization, and complication rates between the compared methods.</p></sec><sec><title>CONCLUSION</title><p>CONCLUSION: Endoscopic surgical treatment of benign prostatic hyperplasia in elderly patients is effective and safe. The choice of technique should be individualized based on patient’s characteristics and disease severity.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>доброкачественная гиперплазия предстательной железы</kwd><kwd>эндоскопическое лечение</kwd><kwd>пожилой возраст</kwd><kwd>уродинамика</kwd></kwd-group><kwd-group xml:lang="en"><kwd>benign prostatic hyperplasia</kwd><kwd>endoscopic treatment</kwd><kwd>elderly patients</kwd><kwd>urodynamics</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ahyai S.A., Gilling P., Kaplan S.A. et al. Meta-analysis of functional outcomes and complications following transurethral procedures for lower urinary tract symptoms resulting from benign prostatic enlargement. Eur Urol 2010;58(3):384–97. DOI: 10.1016/j.eururo.2010.06.005</mixed-citation><mixed-citation xml:lang="en">Ahyai S.A., Gilling P., Kaplan S.A. et al. Meta-analysis of functional outcomes and complications following transurethral procedures for lower urinary tract symptoms resulting from benign prostatic enlargement. Eur Urol 2010;58(3):384–97. DOI: 10.1016/j.eururo.2010.06.005</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Berry S.J., Coffey D.S., Walsh P.C., Ewing L.L. The development of human benign prostatic hyperplasia with age. J Urol 1984;132(3):474–9. DOI: 10.1016/s0022-5347(17)49698-4</mixed-citation><mixed-citation xml:lang="en">Berry S.J., Coffey D.S., Walsh P.C., Ewing L.L. The development of human benign prostatic hyperplasia with age. J Urol 1984;132(3):474–9. DOI: 10.1016/s0022-5347(17)49698-4</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Cornu J.N., Ahyai S., Bachmann A. et al. A systematic review and meta-analysis of functional outcomes and complications following transurethral procedures for lower urinary tract symptoms resulting from benign prostatic obstruction: an update. Eur Urol 2015;67(6):1066–96. DOI: 10.1016/j.eururo.2014.06.017</mixed-citation><mixed-citation xml:lang="en">Cornu J.N., Ahyai S., Bachmann A. et al. A systematic review and meta-analysis of functional outcomes and complications following transurethral procedures for lower urinary tract symptoms resulting from benign prostatic obstruction: an update. Eur Urol 2015;67(6):1066–96. DOI: 10.1016/j.eururo.2014.06.017</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Elzayat E.A., Elhiali M.M. Holmium laser enucleation of the prostate (HoLEP): long-term results, reoperation rate, and possible impact of the learning curve. Eur Urol 2007;52(5):1465–72. DOI: 10.1016/j.eururo.2007.04.074</mixed-citation><mixed-citation xml:lang="en">Elzayat E.A., Elhiali M.M. Holmium laser enucleation of the prostate (HoLEP): long-term results, reoperation rate, and possible impact of the learning curve. Eur Urol 2007;52(5):1465–72. DOI: 10.1016/j.eururo.2007.04.074</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Sandhu J.S., Bixler B.R., Dahm P. et al. Management of lower urinary tract symptoms attributed to benign prostatic hyperplasia (BPH): AUA guideline amendment 2023. J Urol 2024;211(1):11–9. DOI: 10.1097/JU.0000000000003698</mixed-citation><mixed-citation xml:lang="en">Sandhu J.S., Bixler B.R., Dahm P. et al. Management of lower urinary tract symptoms attributed to benign prostatic hyperplasia (BPH): AUA guideline amendment 2023. J Urol 2024;211(1):11–9. DOI: 10.1097/JU.0000000000003698</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Kuntz R.M., Lehrich K., Ahyai S.A. Holmium laser enucleation of the prostate versus open prostatectomy for prostates greater than 100 grams: 5-year follow-up results of a randomised clinical trial. Eur Urol. 2008;53(1):160–6. DOI: 10.1016/j.eururo.2007.08.036</mixed-citation><mixed-citation xml:lang="en">Kuntz R.M., Lehrich K., Ahyai S.A. Holmium laser enucleation of the prostate versus open prostatectomy for prostates greater than 100 grams: 5-year follow-up results of a randomised clinical trial. Eur Urol. 2008;53(1):160–6. DOI: 10.1016/j.eururo.2007.08.036</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">McVary K.T., Roehrborn C.G., Avins A.L. et al. Update on AUA guideline on the management of benign prostatic hyperplasia. J Urol 2011;185(5):1793–803. DOI: 10.1016/j.juro.2011.01.074</mixed-citation><mixed-citation xml:lang="en">McVary K.T., Roehrborn C.G., Avins A.L. et al. Update on AUA guideline on the management of benign prostatic hyperplasia. J Urol 2011;185(5):1793–803. DOI: 10.1016/j.juro.2011.01.074</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
