agxАндрология и генитальная хирургияAndrology and Genital Surgery2070-97812412-890210.63769/2070-9781-2026-27-1-82-95agx-863Research ArticleОБЗОРНЫЕ СТАТЬИREVIEWНовые возможности патогенетической терапии при хроническом простатитеNew opportunities for targeted therapy in patients with chronic prostatitishttps://orcid.org/0000-0001-8062-7775КульчавеняЕ. В.KulchavenyaE. V.

Кульчавеня Екатерина Валерьевна, д.м.н., профессор

Новосибирск

Ekaterina V. Kulchavenya

Novosibirsk

urotub@yandex.ruНовосибирский государственный медицинский университет; Клинический госпиталь «Авиценна»РоссияNovosibirsk State Medical University; Avicenna Clinical HospitalRussian Federation2026090520262718295Copyright © Кульчавеня Е.В., 20262026Кульчавеня Е.В.Kulchavenya E.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://agx.elpub.ru/jour/article/view/863

Проведен аналитический обзор 172 источников отечественной и зарубежной литературы по возможностям патогенетической терапии пациентов с хроническим простатитом/синдромом хронической тазовой боли с помощью многофункциональных нутрицевтиков и микроэлементов, скомпонованных в биологически активном комплексе Кверцепрост: кверцетин, ликопин, нарингин, селен и цинк. Показано многокомпонентное действие Кверцепроста – антимутагенное, противовоспалительное, кардиозащитное и нейропротекторное. Кверцепрост подавляет окислительный стресс, сохраняет оксид азота и целостность эндотелия, модулирует нейрогормональные системы и активирует провыживательные сигналы в клетках, одновременно ингибируя апоптоз, аутофагию и ферроптоз.

This analytical review, synthesizing data from 172 Russian and international studies, explores targeted therapy for chronic prostatitis and chronic pelvic pain syndrome using Querceprost – a multifunctional bioactive complex containing quercetin, lycopene, naringin, selenium, and zinc. The findings highlight multiple effects of Querceprost, including its antimutagenic, anti-inflammatory, cardioprotective, and neuroprotective properties. Querceprost mitigates oxidative stress, preserves nitric oxide and endothelial integrity, and modulates neurohormonal signaling. Furthermore, it promotes pro-survival cellular pathways while simultaneously inhibiting apoptosis, autophagy, and ferroptosis.

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The authors declare that there are no conflicts of interest present.