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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">agx</journal-id><journal-title-group><journal-title xml:lang="ru">Андрология и генитальная хирургия</journal-title><trans-title-group xml:lang="en"><trans-title>Andrology and Genital Surgery</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2070-9781</issn><issn pub-type="epub">2412-8902</issn><publisher><publisher-name></publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17650/2070-9781-2023-24-3-66-74</article-id><article-id custom-type="elpub" pub-id-type="custom">agx-684</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНАЯ СТАТЬЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL REPORT</subject></subj-group></article-categories><title-group><article-title>Оценка функционального состояния почек до и после резекции по поводу односторонней опухоли с помощью математической обработки данных компьютерной томографии с контрастированием</article-title><trans-title-group xml:lang="en"><trans-title>Assessment of the kidney functional state prior and after partial nephrectomy for a unilateral tumor using mathematical processing of computed tomography data with contrast enhancement</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0441-4799</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Проскура</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Proskura</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>119435 Москва, ул. Большая Пироговская, 2, стр. 1; 119435 Москва, ул. Погодинская, 1, стр. 1</p></bio><bio xml:lang="en"><p>Bld. 1, 2 Bolshaya Pirogovskaya St., Moscow 119435; Bld. 1, 1 Pogodinskaya St., Moscow 119435</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2937-0983</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аляев</surname><given-names>Ю. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Alyaev</surname><given-names>Yu. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>119435 Москва, ул. Большая Пироговская, 2, стр. 1</p></bio><bio xml:lang="en"><p>Bld. 1, 2 Bolshaya Pirogovskaya St., Moscow 119435</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Борисов</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Borisov</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>119435 Москва, ул. Большая Пироговская, 2, стр. 1</p></bio><bio xml:lang="en"><p>Bld. 1, 2 Bolshaya Pirogovskaya St., Moscow 119435</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2173-0566</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бутнару</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Butnaru</surname><given-names>D. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>119435 Москва, ул. Большая Пироговская, 2, стр. 1</p></bio><bio xml:lang="en"><p>Bld. 1, 2 Bolshaya Pirogovskaya St., Moscow 119435</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7787-1240</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рапопорт</surname><given-names>Л. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Rapoport</surname><given-names>L. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>119435 Москва, ул. Большая Пироговская, 2, стр. 1</p></bio><bio xml:lang="en"><p>Bld. 1, 2 Bolshaya Pirogovskaya St., Moscow 119435</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6419-0155</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сирота</surname><given-names>Е. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Sirota</surname><given-names>E. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>119435 Москва, ул. Большая Пироговская, 2, стр. 1</p></bio><bio xml:lang="en"><p>Bld. 1, 2 Bolshaya Pirogovskaya St., Moscow 119435</p></bio><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2224-0019</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Суворов</surname><given-names>А. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Suvorov</surname><given-names>A. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>119435 Москва, ул. Большая Пироговская, 2, стр. 1</p></bio><bio xml:lang="en"><p>Bld. 1, 2 Bolshaya Pirogovskaya St., Moscow 119435</p></bio><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0401-8780</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фиев</surname><given-names>Д. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Fiev</surname><given-names>D. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>119435 Москва, ул. Большая Пироговская, 2, стр. 1; 119435 Москва, ул. Погодинская, 1, стр. 1; 119435 Москва, ул. Большая Пироговская, 2, стр. 1</p></bio><bio xml:lang="en"><p>Bld. 1, 2 Bolshaya Pirogovskaya St., Moscow 119435; Bld. 1, 1 Pogodinskaya St., Moscow 119435; Bld. 1, 2 Bolshaya Pirogovskaya St., Moscow 119435</p></bio><xref ref-type="aff" rid="aff-6"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1121-9430</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шпоть</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shpot</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>119435 Москва, ул. Большая Пироговская, 2, стр. 1; 119435 Москва, ул. Погодинская, 1, стр. 1</p></bio><bio xml:lang="en"><p>Bld. 1, 2 Bolshaya Pirogovskaya St., Moscow 119435; Bld. 1, 1 Pogodinskaya St., Moscow 119435</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2746-5962</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Безруков</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Bezrukov</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>119435 Москва, ул. Большая Пироговская, 2, стр. 1; 119435 Москва, ул. Погодинская, 1, стр. 1</p></bio><bio xml:lang="en"><p>Bld. 1, 2 Bolshaya Pirogovskaya St., Moscow 119435; Bld. 1, 1 Pogodinskaya St., Moscow 119435</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3007-1315</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Еникеев</surname><given-names>М. Э.</given-names></name><name name-style="western" xml:lang="en"><surname>Enikeev</surname><given-names>M. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>119435 Москва, ул. Большая Пироговская, 2, стр. 1; 119435 Москва, ул. Погодинская, 1, стр. 1</p></bio><bio xml:lang="en"><p>Bld. 1, 2 Bolshaya Pirogovskaya St., Moscow 119435; Bld. 1, 1 Pogodinskaya St., Moscow 119435</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1583-6121</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Акопян</surname><given-names>Г. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Akopyan</surname><given-names>G. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>119435 Москва, ул. Большая Пироговская, 2, стр. 1</p></bio><bio xml:lang="en"><p>Bld. 1, 2 Bolshaya Pirogovskaya St., Moscow 119435</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8861-8187</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Королев</surname><given-names>Д. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Korolev</surname><given-names>D. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Королев Дмитрий Олегович.</p><p>119435 Москва, ул. Большая Пироговская, 2, стр. 1</p></bio><bio xml:lang="en"><p>Dmitriy O. Korolev.</p><p>Bld. 1, 2 Bolshaya Pirogovskaya St., Moscow 119435</p></bio><email xlink:type="simple">korolevdmitryo@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Воробьев</surname><given-names>A. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Vorobiev</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>119435 Москва, ул. Большая Пироговская, 2, стр. 1; 119435 Москва, ул. Погодинская, 1, стр. 1</p></bio><bio xml:lang="en"><p>Bld. 1, 2 Bolshaya Pirogovskaya St., Moscow 119435</p></bio><xref ref-type="aff" rid="aff-7"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4001-5317</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Черненький</surname><given-names>М. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Chernenkiy</surname><given-names>M. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>119435 Москва, ул. Большая Пироговская, 2, стр. 1</p></bio><bio xml:lang="en"><p>Bld. 1, 2 Bolshaya Pirogovskaya St., Moscow 119435</p></bio><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5968-9883</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Черненький</surname><given-names>И. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Chernenkiy</surname><given-names>I. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>119435 Москва, ул. Большая Пироговская, 2, стр. 1</p></bio><bio xml:lang="en"><p>Bld. 1, 2 Bolshaya Pirogovskaya St., Moscow 119435</p></bio><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0548-190X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Исмаилов</surname><given-names>Х. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Ismailov</surname><given-names>Kh. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>119435 Москва, ул. Большая Пироговская, 2, стр. 1</p></bio><bio xml:lang="en"><p>Bld. 1, 2 Bolshaya Pirogovskaya St., Moscow 119435</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0009-7685-0902</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шомукимова</surname><given-names>З. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Shomukimova</surname><given-names>Z. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>119435 Москва, ул. Большая Пироговская, 2, стр. 1</p></bio><bio xml:lang="en"><p>Bld. 1, 2 Bolshaya Pirogovskaya St., Moscow 119435</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Институт урологии и репродуктивного здоровья человека ФГАОУ ВО Первый Московский государственный медицинский университет им. И.М. Сеченова Минздрава России (Сеченовский Университет); Университетская клиническая больница № 2 ФГАОУ ВО Первый Московский государственный медицинский университет им. И.М. Сеченова Минздрава России (Сеченовский Университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Institute of Urology and Human Reproductive Health, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University); University Clinical Hospital No. 2 of the I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Институт урологии и репродуктивного здоровья человека ФГАОУ ВО Первый Московский государственный медицинский университет им. И.М. Сеченова Минздрава России (Сеченовский Университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Institute of Urology and Human Reproductive Health, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Российское общество урологов</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Association of Urology</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Центр нейросетевых технологий Института урологии и репродуктивного здоровья человека ФГАОУ ВО Первый Московский государственный медицинский университет им. И.М. Сеченова Минздрава России (Сеченовский Университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Center for Neural Network Technologies of the Research Institute of Uronephrology and Human Reproductive Health, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>Центр анализа сложных систем Института биодизайна и моделирования сложных систем ФГАОУ ВО Первый Московский государственный медицинский университет им. И.М. Сеченова Минздрава России (Сеченовский Университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Center for Analysis of Complex Systems of the Institute of Biodesign and Modeling of Complex Systems, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-6"><aff xml:lang="ru"><institution>Институт урологии и репродуктивного здоровья человека ФГАОУ ВО Первый Московский государственный медицинский университет им. И.М. Сеченова Минздрава России (Сеченовский Университет); Университетская клиническая больница № 2 ФГАОУ ВО Первый Московский государственный медицинский университет им. И.М. Сеченова Минздрава России (Сеченовский Университет); Центр нейросетевых технологий Института урологии и репродуктивного здоровья человека ФГАОУ ВО Первый Московский государственный медицинский университет им. И.М. Сеченова Минздрава России (Сеченовский Университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Institute of Urology and Human Reproductive Health, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University); University Clinical Hospital No. 2 of the I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University); Center for Neural Network Technologies of the Research Institute of Uronephrology and Human Reproductive Health, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-7"><aff xml:lang="ru"><institution>Институт урологии и репродуктивного здоровья человека ФГАОУ ВО Первый Московский государственный медицинский университет им. И.М. Сеченова Минздрава России (Сеченовский Университет); Университетская клиническая больница № 2 ФГАОУ ВО Первый Московский государственный медицинский университет им. И.М. Сеченова Минздрава России (Сеченовский Университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Institute of Urology and Human Reproductive Health, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>11</day><month>09</month><year>2023</year></pub-date><volume>24</volume><issue>3</issue><fpage>66</fpage><lpage>74</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Проскура А.В., Аляев Ю.Г., Борисов В.В., Бутнару Д.В., Рапопорт Л.М., Сирота Е.С., Суворов А.Ю., Фиев Д.Н., Шпоть Е.В., Безруков Е.А., Еникеев М.Э., Акопян Г.Н., Королев Д.О., Воробьев A.А., Черненький М.М., Черненький И.М., Исмаилов Х.М., Шомукимова З.С., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Проскура А.В., Аляев Ю.Г., Борисов В.В., Бутнару Д.В., Рапопорт Л.М., Сирота Е.С., Суворов А.Ю., Фиев Д.Н., Шпоть Е.В., Безруков Е.А., Еникеев М.Э., Акопян Г.Н., Королев Д.О., Воробьев A.А., Черненький М.М., Черненький И.М., Исмаилов Х.М., Шомукимова З.С.</copyright-holder><copyright-holder xml:lang="en">Proskura A.V., Alyaev Y.G., Borisov V.V., Butnaru D.V., Rapoport L.M., Sirota E.S., Suvorov A.Y., Fiev D.N., Shpot E.V., Bezrukov E.A., Enikeev M.E., Akopyan G.N., Korolev D.O., Vorobiev A.A., Chernenkiy M.M., Chernenkiy I.M., Ismailov K.M., Shomukimova Z.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://agx.elpub.ru/jour/article/view/684">https://agx.elpub.ru/jour/article/view/684</self-uri><abstract><sec><title>Введение</title><p>Введение. По данным работ отечественных и зарубежных авторов, мультиспиральная компьютерная томография (МСКТ) с контрастированием может быть использована для оценки суммарной и раздельной функции почек. В клинике урологии ФГАОУ ВО Первый МГМУ им. И.М. Сеченова Минздрава России (Сеченовский Университет) успешно применяется метод математического анализа данных МСКТ с контрастированием в оценке раздельной функции почек.</p><p>Цель исследования – оценить влияние пережатия основной почечной артерии при резекции почки по поводу односторонней опухоли почки на динамику суммарных и раздельных функциональных почечных показателей.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. В исследование были включены 33 пациента обоего пола, которым по поводу одностороннего образования почки выполнена ее резекция на фоне пережатия основной почечной артерии. До и через 3–6 мес после оперативного вмешательства с целью оценки раздельной почечной функции выполняли математический анализ данных МСКТ почек с контрастированием (определяли такие показатели, как трехмерная (3D) скорость клубочковой фильтрации (СКФ), 3D-перфузия, 3D-объем функционирующей паренхимы почек). Помимо этого, исследовали динамику суммарной скорости клубочковой фильтрации, основанной на применении расчетной формулы, а также суммарный 3D-объем почек и показатель динамики уровня креатинина крови.</p></sec><sec><title>Результаты</title><p>Результаты. Не было получено значимой динамики как для общих функциональных почечных показателей (уровень креатинина, суммарная СКФ, суммарный объем функционирующей паренхимы почек), так и для раздельной 3D-СКФ. Отмечались значимые различия в динамике для таких раздельных функциональных почечных показателей, как 3D-перфузия и объем функционирующей паренхимы почек.</p></sec><sec><title>Выводы</title><p>Выводы. Полученные результаты позволяют судить о хороших резервных и компенсаторных возможностях почек после их резекции по поводу опухоли. Подтверждением того, что не прооперированная почка берет на себя функцию другой, служит то, что происходит увеличение ее перфузии и объема функционирующей паренхимы в послеоперационном периоде. Данный процесс может расцениваться и как перераспределение функциональных нагрузок между почками, что является адаптационным механизмом в послеоперационном периоде.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Background</title><p>Background. According to the contemporary data available contrast-enhanced computed tomography can be used to assess total and split kidney function. The Urology Clinic of the I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University) utilizes mathematical processing of computed tomography data for the assessment of split kidney function.</p></sec><sec><title>Aim</title><p>Aim. To evaluate the effect of main renal artery clamping (warm ischemia time) during partial nephrectomy for a unilateral tumor on the kidney function.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. 33 patients of both sexes who underwent partial nephrectomy for unilateral kidney tumor were enrolled in the study. Prior to and 3–6 months after the surgery, 3D glomerular filtration rate (GFR), 3D perfusion, 3D volume of the renal parenchyma were evaluated by mathematical processing of computed tomography data with contrast enhancement. As well as that the dynamics of the total GFR (CKD-EPI equation) and total volume of the kidneys were assessed.</p></sec><sec><title>Results</title><p>Results. No significant changes were registered for both general functional renal parameters (creatinine level, total GFR, total volume of functioning renal parenchyma) and split 3D GFR. There were significant differences in 3D perfusion and kidney parenchyma volume prior and after partial nephrectomy.</p></sec><sec><title>Conclusion</title><p>Conclusion. The results of the research highlight good reserve capacity the kidneys after partial nephrectomy with main renal artery clamping. The evidence that the non-operated kidney takes over the function of the resected kidney is based on the fact that there is an increase in its perfusion and volume of the kidney in the postoperative period. This state can also be regarded as a redistribution of functional loads between the kidneys, which is an adaptive mechanism in the postoperative period.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>опухоль почки</kwd><kwd>функция</kwd><kwd>компьютерная томография</kwd><kwd>клубочковая фильтрация</kwd></kwd-group><kwd-group xml:lang="en"><kwd>kidney tumor</kwd><kwd>renal function</kwd><kwd>computed tomography</kwd><kwd>glomerular filtration</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Campbell S.C., Novick A.C., Belldegrun A. et al. Guideline for management of the clinical T1 renal mass. J Urol 2009;182(4):1271–9. DOI: 10.1016/j.juro.2009.07.004</mixed-citation><mixed-citation xml:lang="en">Campbell S.C., Novick A.C., Belldegrun A. et al. Guideline for management of the clinical T1 renal mass. J Urol 2009;182(4):1271–9. 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