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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">agx</journal-id><journal-title-group><journal-title xml:lang="ru">Андрология и генитальная хирургия</journal-title><trans-title-group xml:lang="en"><trans-title>Andrology and Genital Surgery</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2070-9781</issn><issn pub-type="epub">2412-8902</issn><publisher><publisher-name></publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17650/2070-9781-2017-18-3-83-88</article-id><article-id custom-type="elpub" pub-id-type="custom">agx-252</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ХИРУРГИЧЕСКАЯ ТЕХНИКА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>SURGICAL TECHNIQUE</subject></subj-group></article-categories><title-group><article-title>ЭНДОСКОПИЧЕСКАЯ ЭНУКЛЕАЦИЯ ПРЕДСТАТЕЛЬНОЙ ЖЕЛЕЗЫ – НОВЫЙ СТАНДАРТ ХИРУРГИЧЕСКОГО ЛЕЧЕНИЯ ГИПЕРПЛАЗИИ ПРЕДСТАТЕЛЬНОЙ ЖЕЛЕЗЫ</article-title><trans-title-group xml:lang="en"><trans-title>ENDOSCOPIC ENUCLEATION OF THE PROSTATE – A NEW STANDARD IN SURGICAL TREATMENT OF BENIGN PROSTATIC HYPERPLASIA</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Еникеев</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Enikeev</surname><given-names>D. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>119435 Москва, ул. Большая Пироговская, 2, стр. 1</p></bio><bio xml:lang="en"><p>Build. 2, 1 Bol’shaya Pirogovskaya St., Moscow 119435</p></bio><email xlink:type="simple">enikeev_dv@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Глыбочко</surname><given-names>П. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Glybochko</surname><given-names>P. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>119435 Москва, ул. Большая Пироговская, 2, стр. 1</p></bio><bio xml:lang="en"><p>Build. 2, 1 Bol’shaya Pirogovskaya St., Moscow 119435</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аляев</surname><given-names>Ю. Г</given-names></name><name name-style="western" xml:lang="en"><surname>Alyaev</surname><given-names>Yu. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>119435 Москва, ул. Большая Пироговская, 2, стр. 1</p></bio><bio xml:lang="en"><p>Build. 2, 1 Bol’shaya Pirogovskaya St., Moscow 119435</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рапопорт</surname><given-names>Л. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Rapoport</surname><given-names>L. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>119435 Москва, ул. Большая Пироговская, 2, стр. 1</p></bio><bio xml:lang="en"><p>Build. 2, 1 Bol’shaya Pirogovskaya St., Moscow 119435</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Еникеев</surname><given-names>М. Э.</given-names></name><name name-style="western" xml:lang="en"><surname>Enikeev</surname><given-names>M. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>119435 Москва, ул. Большая Пироговская, 2, стр. 1</p></bio><bio xml:lang="en"><p>Build. 2, 1 Bol’shaya Pirogovskaya St., Moscow 119435</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Спивак</surname><given-names>Л. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Spivak</surname><given-names>L. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>119435 Москва, ул. Большая Пироговская, 2, стр. 1</p></bio><bio xml:lang="en"><p>Build. 2, 1 Bol’shaya Pirogovskaya St., Moscow 119435</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Цариченко</surname><given-names>Д. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Tsarichenko</surname><given-names>D. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>119435 Москва, ул. Большая Пироговская, 2, стр. 1</p></bio><bio xml:lang="en"><p>Build. 2, 1 Bol’shaya Pirogovskaya St., Moscow 119435</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сорокин</surname><given-names>Н. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Sorokin</surname><given-names>N. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>119435 Москва, ул. Большая Пироговская, 2, стр. 1</p></bio><bio xml:lang="en"><p>Build. 2, 1 Bol’shaya Pirogovskaya St., Moscow 119435</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Суханов</surname><given-names>Р. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Sukhanov</surname><given-names>R. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>119435 Москва, ул. Большая Пироговская, 2, стр. 1</p></bio><bio xml:lang="en"><p>Build. 2, 1 Bol’shaya Pirogovskaya St., Moscow 119435</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дымов</surname><given-names>А М.</given-names></name><name name-style="western" xml:lang="en"><surname>Dymov</surname><given-names>A. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>119435 Москва, ул. Большая Пироговская, 2, стр. 1</p></bio><bio xml:lang="en"><p>Build. 2, 1 Bol’shaya Pirogovskaya St., Moscow 119435</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хамраев</surname><given-names>О. Х.</given-names></name><name name-style="western" xml:lang="en"><surname>Khamraev</surname><given-names>O. Kh.</given-names></name></name-alternatives><bio xml:lang="ru"><p>119435 Москва, ул. Большая Пироговская, 2, стр. 1</p></bio><bio xml:lang="en"><p>Build. 2, 1 Bol’shaya Pirogovskaya St., Moscow 119435</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гаас</surname><given-names>М. Я.</given-names></name><name name-style="western" xml:lang="en"><surname>Gaas</surname><given-names>M. Ya.</given-names></name></name-alternatives><bio xml:lang="ru"><p>119435 Москва, ул. Большая Пироговская, 2, стр. 1</p></bio><bio xml:lang="en"><p>Build. 2, 1 Bol’shaya Pirogovskaya St., Moscow 119435</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тараткин</surname><given-names>М. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Taratkin</surname><given-names>M. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>119435 Москва, ул. Большая Пироговская, 2, стр. 1</p></bio><bio xml:lang="en"><p>Build. 2, 1 Bol’shaya Pirogovskaya St., Moscow 119435</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>НИИ уронефрологии и репродуктивного здоровья человека ФГБОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research Institute of Uronephrology and Human Reproductive Health of I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>11</day><month>11</month><year>2017</year></pub-date><volume>18</volume><issue>3</issue><fpage>83</fpage><lpage>88</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Еникеев Д.В., Глыбочко П.В., Аляев Ю.Г., Рапопорт Л.М., Еникеев М.Э., Спивак Л.Г., Цариченко Д.Г., Сорокин Н.И., Суханов Р.Б., Дымов А.М., Хамраев О.Х., Гаас М.Я., Тараткин М.С., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Еникеев Д.В., Глыбочко П.В., Аляев Ю.Г., Рапопорт Л.М., Еникеев М.Э., Спивак Л.Г., Цариченко Д.Г., Сорокин Н.И., Суханов Р.Б., Дымов А.М., Хамраев О.Х., Гаас М.Я., Тараткин М.С.</copyright-holder><copyright-holder xml:lang="en">Enikeev D.V., Glybochko P.V., Alyaev Y.G., Rapoport L.M., Enikeev M.E., Spivak L.G., Tsarichenko D.G., Sorokin N.I., Sukhanov R.B., Dymov A.M., Khamraev O.K., Gaas M.Y., Taratkin M.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://agx.elpub.ru/jour/article/view/252">https://agx.elpub.ru/jour/article/view/252</self-uri><abstract><p>В последних рекомендациях Европейской ассоциации урологов (2016) по лечению симптомов со стороны нижних мочевыводящих путей, вызванных гиперплазией предстательной железы (ПЖ), описан новый термин – endoscopic enucleation of the prostate (эндоскопическая энуклеация ПЖ). Своим появлением этот термин обязан данным последних метаанализов, доказавших, что как лазерная энуклеация, так и электроэнуклеация являются эффективными методиками лечения инфравезикальной обструкции, вызванной гиперплазией ПЖ.</p><p>Цель исследования – сравнить методы электроэнуклеации и лазерных энуклеаций (тулиевая, гольмиевая) гиперплазии ПЖ по данным литературных источников и собственным наблюдениям.</p><sec><title>Материалы и методы</title><p>Материалы и методы. В исследовании приняли участие 624 пациента с доброкачественной гиперплазией ПЖ; из них 459 пациентов перенесли гольмиевую энуклеацию (holmium laser enucleation of the prostate, HoLEP), 35 – монополярную энуклеацию, 130 – тулиевую энуклеацию (thulium laser enucleation of the prostate, ThuLEP). Срок наблюдения за всеми пациентами составил 1 мес. Нами была проведена оценка показателя по опроснику IPSS (International Prostate Symptom Score), индекса качества жизни (QoL), максимальной объемной скорости потока мочи (Qmax) и объема остаточной мочи перед операцией и через месяц после нее.</p></sec><sec><title>Результаты</title><p>Результаты. Функциональные результаты через 1 мес после операции во всех 3 группах показали значимое улучшение. Более того, полученные данные указывают на одинаковую сравнительную эффективность методов эндоскопической энуклеации. Не было выявлено статистически значимого отклонения ни по одному из исследуемых параметров (p &gt;0,05).</p></sec><sec><title>Выводы</title><p>Выводы. Данные наших практических работ по HoLEP и ThuLEP указывают на высокую эффективность этих операций и низкое количество послеоперационных осложнений, что находится в соответствии с данными литературы и рекомендациями Европейской ассоциации урологов. Монополярная энуклеация ПЖ не уступает ThuLEP и HoLEP по эффективности, но уступает по количеству послеоперационных осложнений. </p></sec></abstract><trans-abstract xml:lang="en"><p>The latest guideline of the European Association of Urology (2016) for the management of lower urinary tract symptoms has a new term – endoscopic enucleation of the prostate. This term was introduced after the publication of latest meta-analyses showing that both laser enucleation and electroenucleation are effective in the treatment of infravesical obstruction caused by benign prostatic hyperplasia (BPH).</p><sec><title>Objective</title><p>Objective: to compare the methods of electroenucleation and laser enucleation (holmium and thulium) of the prostate according to the literature data and own observations.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. A total of 624 patients with BPH were included in the study; of them, 459 participants underwent holmium laser enucleation (HoLEP), 35 – monopolar enucleation, and 130 – thulium laser enucleation (ThuLEP). All patients were followed up for one month. We assessed the International Prostate Symptom Score (IPSS), patients’ quality of life (QoL), peak flow rate (Qmax), and residual urine volume prior to surgery and 1 month after it.</p></sec><sec><title>Results</title><p>Results. Functional characteristics have significantly improved by one month post surgery in all three groups. Moreover, the data obtained indicate similar efficacy of different endoscopic enucleation methods. None of the tested parameters demonstrated significant difference across the groups (p &gt;0.05)</p></sec><sec><title>Conclusions</title><p>Conclusions. Our results of HoLEP and ThuLEP suggest high efficacy of these surgical techniques and low number of postoperative complications, which correlates with literature data and guidelines of the European Association of Urology. Monopolar enucleation of the prostate is as effective as ThuLEP or HoLEP; however it has higher frequency of postoperative complications.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>ThuLEP</kwd><kwd>HoLEP</kwd><kwd>лазерная энуклеация</kwd><kwd>монополярная энуклеация</kwd><kwd>удаление аденомы предстательной железы</kwd><kwd>инфравезикальная обструкция</kwd><kwd>доброкачественная гиперплазия предстательной железы</kwd></kwd-group><kwd-group xml:lang="en"><kwd>ThuLEP</kwd><kwd>HoLEP</kwd><kwd>laser enucleation</kwd><kwd>monopolar enucleation</kwd><kwd>removal of prostate adenoma</kwd><kwd>infravesical obstruction</kwd><kwd>benign prostatic hyperplasia</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Kaplan S.A. Re: EAU Guidelines on the Assessment of Non-Neurogenic Male Lower Urinary Tract Symptoms Including Benign Prostatic Obstruction. 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